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When you take a medicine (or drug), your body needs to find a way to use it.  Some proteins in your body carry (transport) medicines so that they can be used.  If your body can’t carry a medicine to the right place, this may make the medicine not work as well.  It may also cause a side effect.

The ABCG2 (say "AY-BEE-SEE-JEE-2") gene helps your body make a protein the carries certain medicines, including:

• Rosuvastatin (for lowering cholesterol) 

This is the medicine that we know of right now that is impacted by ABCG2 gene test results.  Medical experts keep finding new data about which medicines are affected by gene test results.

By testing your DNA, we can find DNA differences.  This can help us to see how well the proteins in your body work to carry different medicines. 

The results of your ABCG2 gene test will place you into 1 of 3 groups:

• Normal function: Your ABCG2 proteins likely work normally. 
• Decreased function: Your ABCG2 proteins may not work as well as they should. 
• Poor function: Your ABCG2 proteins may or may not work at all.

The results of this test can help your doctor choose the right medicine and dose for you.