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When you take a medicine (or drug), your body needs to find a way to use it.  Some proteins in your body break down (or metabolize) medicines.  Breaking down a medicine can make it more active or less active, based on what kind of medicine you are taking.  If your body breaks down a medicine too quickly or too slowly, this may make the medicine not work as well.  It may also cause a side effect.

The CYP2C19 (say "SIP-2-SEE-19") gene helps your body make a protein that breaks down certain medicines, including: 

These are the medicines that we know of right now that are impacted by CYP2C19 gene test results.  Medical experts keep finding new data about which medicines are affected by gene test results. 

By testing your DNA, we can find DNA differences.  This can help us to see how well the proteins in your body work to break down certain medicines. 

The results of your CYP2C19 gene test put you into 1 of 5 groups:

• Normal metabolizer: Your CYP2C19 proteins likely work normally. 
• Intermediate metabolizer: Your CYP2C19 proteins likely have reduced activity. 
• Poor metabolizer: Your CYP2C19 proteins may or may not work at all. 
• Rapid metabolizer: Your CYP2C19 proteins likely have high activity. 
• Ultrarapid metabolizer: Your CYP2C19 proteins likely have very high activity. 

The results of this test can help your doctor choose the right medicine and dose for you.